Mucosal melanosis and hamartomatous polyps are seen in?
Correct Answer: Peutz-Jeghers syndrome
Description: Ref: Harrison 19th ed., P 240* Peutz-Jeghers syndrome is characterized by dark brown spots on lips, buccal mucosa, nose and around eyes. There is concomitant intestinal polyposis. The most common location of polyps is in jejunum.* It is an autosomal dominant disorder with STK11 mutation.* The malignant potential of polyps ranges from never to rare transformation.
Category:
Pathology
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