Mucosal melanosis and hamaomatous polyps are seen in?
Correct Answer: Peutz-Jeghers syndrome
Description: Peutz-jeghers syndrome: Autosomal dominant disorder Mutation- STK 11 / LKB1 gene Multiple gastrointestinal hamaomatous polyps + Mucocutaneous hyperpigmentation Increased risk for colon, pancreas, breast, lung, ovaries, uterus, testes neoplasms Gross- Polyps are large & pedunculated with lobulated contour.
Category:
Pathology
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