Mucosal invasion of intestine causes which type of diarrhea
**Core Concept**
Mucosal invasion of the intestine, as seen in conditions like invasive amoebiasis or invasive bacterial infections, disrupts the normal absorptive and secretory functions of the intestinal mucosa. This disruption leads to an imbalance in the electrolyte and fluid transport across the intestinal epithelium, resulting in diarrhea.
**Why the Correct Answer is Right**
When the intestinal mucosa is invaded, the normal absorptive processes are compromised, and the secretory processes are unopposed. The invading pathogens can cause damage to the intestinal villi and crypts, leading to an increase in the secretion of water and electrolytes into the intestinal lumen. This results in a rapid increase in the volume of intestinal contents, causing diarrhea. The damaged mucosa also impairs the normal absorption of electrolytes and fluids, contributing to the development of diarrhea.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it refers to a type of diarrhea caused by a rapid increase in the absorption of fluids and electrolytes, which is not related to mucosal invasion.
**Option B:** This option is incorrect because it refers to a type of diarrhea caused by an imbalance in the gut microbiota, which is not directly related to mucosal invasion.
**Option C:** This option is incorrect because it refers to a type of diarrhea caused by an increase in the motility of the intestinal muscles, which is not directly related to mucosal invasion.
**Clinical Pearl / High-Yield Fact**
The type of diarrhea caused by mucosal invasion is often characterized by blood and mucus in the stool, and may be accompanied by abdominal pain and weight loss.
**Correct Answer:** D. Invasive diarrhea