Mouse is used for pathogenicity testing in ?
Correct Answer: Bordetella peussis
Description: Ans. is 'c' i.e., Bordetella peussis Bordetella peussis is an obligate human parasite, but infection can be produced experimentally in several species of animals, the white mouse being most often employed. Intranasal inoculation produces a patchy interstitial pneumonia. Intraperitoneal inoculation of large doses is fatal due to toxemia. Intracerebral inoculation causes a fatal infection. Immunized mice are protected. This forms the basis for intracerebral mouse potency assay for peussis vaccines.
Category:
Microbiology
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