Most sensitive test for the diagnosis of herpes simplex (HSV) encephalitis is?
Correct Answer: HSV polymerase chain reaction
Description: Ans. D. HSV polymerase chain reactiona. HSV encephalitis is the most common cause of acute sporadic encephalitis in the world.b. 95% of cases are due to HSV1.c. Age distribution appears to be biphasic, with peaks at ages 5 to 30 years and more than 50 years of age.d. It may follow a primary infection/reactivation of latent virus in the neurons.e. HSV meningitis or encephalitis is difficult to diagnose by laboratory tests, as there is a low titer of virus present in the cerebrospinal fluid.f. Only PCR is sensitive enough to detect HSV DNA in the CSF.
Category:
Microbiology
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