Most important vitamin, w hich promotes wound healing –
Correct Answer: Vitamin C
Description: Ans, is 'a' i.e,, Vitamin Co Vitamin C is required for collagen synthesis.o Due to its important role in collagen synthesis, vitamin C is required for adequate wound healing.Vitamin C (ascorbic acid)o Ascorbic acid (Vitamin C) is also called antiscorbutic factor,o It is very heat labile, especially in basic medium,o Ascorbic acid itself is an active form.o Maximum amount of vitamin C is found in adrenal cortex.o Ascorbic acid functions as a reducing agent and scavanger of free radicals (antioxidant). Its major functions are :-In collagen synthesis Vitamin C is required for post-translational modification by hydroxylation of proline and lysine residues converting them into hydroxyproline and hydroxylysine. Thus vitamin C is essential for the conversion of procollagen to collagen, which is rich in hydroxyproline and hydroxylysine. Through collagen synthesis, it plays a role in formation of matrix of bone, cartilage, dentine and connective tissue.Synthesis of norepinephrine from dopamine by dopamine-b-monoxygenase (dopamine-b-hydroxylase) requires Vitamin C.Carnitine synthesisBile acid synthesis :- 7-a-hvdroxylase requires vitamin C.Absorption of iron is stimulated by ascorbic acid by conversion of ferric to ferrous ions.During adrenal steroid synthesis, ascorbic acid is required during hydroxylation reactions.Tyrosine metabolism : - Oxidation of P-hydroxy-phenylpyruvate to homogentisate.Folate metabolism : - Folic acid is converted to its active form tetrahydrofolate by help of Vitamin C.
Category:
Biochemistry
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