Most impoant antigen initiating graft rejection –
Correct Answer: MHC - molecule
Description: Reference :Robbins basic pathology 9th edition pg no 136 : the most impoant consequence of direct recognition is the activation of CD8+ T cells which recognise class I MHC molecules in the graft.Host CD4+ helper T cell may be triggered into proliferation and cytokine production by recognition of donor class II MHC molecules and drive an inflammatory response
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Pathology
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