Most common type of human papilloma virus causing Ca cervix are:
Correct Answer: 16 and 18
Description: It is now established that HPV plays a major role in cervical carcinogenesis.
Among the various genotypes (more than 100) the Genotype of HPV which is:
Most commonly associated with squamous cell carcinoma cervix - HPV 16
Most common genotype associated with adenocarcinoma of cervix - HPV 18
Overall MC genotype associated with invasive carcinoma, CIN II and CIN III - HPV 16
But HPV 16 is not very specific as it is seen in 16% of women with low grade lesion and 14% women with normal cytology so: - HPV 18
Most specific genotype of HPV for invasive tumor
The cytological changes caused by HPV are collectively called as Koilocytosis.
In most of the females HPV infection clears in 9-15 months , only in small minority it persists.
Malignant transformation requires expression of E6 and E7 HPV oncoproteins.
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now