**Core Concept**
Osteosarcoma is a type of malignant bone tumor characterized by the uncontrolled growth of osteoid tissue, which is the precursor to bone matrix. This tumor arises from the mesenchymal cells that give rise to bone and cartilage.
**Why the Correct Answer is Right**
The most common malignant bone tumor, osteosarcoma, typically presents in the metaphysis of long bones, particularly around the knee. It is associated with a high degree of cellular atypia, mitotic activity, and a tendency to invade surrounding tissues. Osteosarcoma often produces a characteristic "sunburst" appearance on radiographs due to the formation of new bone by the tumor cells.
**Why Each Wrong Option is Incorrect**
**Option A:** Chondrosarcoma is a malignant tumor of cartilage origin, but it is less common than osteosarcoma and typically presents in the pelvis or ribs.
**Option B:** Ewing's sarcoma is a malignant bone tumor, but it is more common in children and adolescents and tends to present in the diaphysis of long bones.
**Option C:** Multiple myeloma is a malignant plasma cell tumor that affects the bone marrow, but it is not a primary bone tumor and typically presents with lytic lesions and anemia.
**Clinical Pearl / High-Yield Fact**
Osteosarcoma often metastasizes to the lungs and has a characteristic "pulmonary metastatic pattern" known as the "moth-eaten" appearance.
**Correct Answer: A. Osteosarcoma**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.