Most common lymph node involved in Hodgkin’s lymphoma is
**Core Concept**
Hodgkin's lymphoma is a type of lymphoma characterized by the presence of Reed-Sternberg cells. It primarily affects the lymphatic system, with lymph nodes being the most common site of involvement.
**Why the Correct Answer is Right**
The most common lymph node involved in Hodgkin's lymphoma is the **cervical lymph node**. This is due to the fact that the disease often originates in the neck region and spreads to the cervical lymph nodes. The involvement of the cervical lymph nodes is a hallmark of Hodgkin's lymphoma and is often used as a diagnostic criterion. The lymph nodes in the neck are also the first point of contact for the immune system to encounter any pathogens or abnormal cells that may have entered the body through the respiratory or gastrointestinal tract.
**Why Each Wrong Option is Incorrect**
**Option A:** Supraclavicular lymph nodes are involved in a more advanced stage of the disease, often indicating a poorer prognosis. They are not the most common site of involvement.
**Option B:** Axillary lymph nodes are more commonly involved in non-Hodgkin lymphoma, particularly in the context of breast cancer. They are not the primary site of involvement in Hodgkin's lymphoma.
**Option C:** Inguinal lymph nodes are more commonly involved in conditions such as lymphogranuloma venereum or filariasis. They are not the most common site of involvement in Hodgkin's lymphoma.
**Clinical Pearl / High-Yield Fact**
The involvement of the cervical lymph nodes in Hodgkin's lymphoma is often associated with a more favorable prognosis compared to other sites of involvement.
**Correct Answer:** C. Cervical lymph node.