Most common cause of Krukenberg’s tumor is?
**Core Concept**
Krukenberg's tumor refers to a metastatic tumor in the ovary, typically originating from a primary site elsewhere in the body. The underlying principle involves the spread of malignant cells to the ovaries, often through lymphatic or hematogenous routes. This phenomenon is observed in **gastrointestinal cancers**, among others.
**Why the Correct Answer is Right**
The most common cause of Krukenberg's tumor is **gastric carcinoma**, which metastasizes to the ovaries. This occurs due to the dissemination of malignant cells from the stomach to the ovaries, often facilitated by lymphatic or vascular pathways. The **Krukenberg cells**, characteristic of this condition, are mucin-filled, signet-ring shaped cells.
**Why Each Wrong Option is Incorrect**
**Option A:** Incorrect as it is not the most common cause.
**Option B:** Incorrect, though it can be a cause, it is less common than gastric carcinoma.
**Option C:** Incorrect, not typically associated with Krukenberg's tumor.
**Option D:** Incorrect, while it can metastasize, it is not the most common source.
**Clinical Pearl / High-Yield Fact**
Krukenberg's tumor is a significant clinical entity, as it often presents with abdominal symptoms and can be mistaken for a primary ovarian tumor. Recognizing the signet-ring cell morphology is crucial for diagnosis.
**Correct Answer:** D. Gastric carcinoma.