Most common cause of genu valgum in children is –
Wait, let me think again. Rickets can cause both genu varum and genu valgum depending on the stage. Early stages might present with bowlegs, and later with knock-knees. But in children, the most common cause is usually rickets. Are there other causes? Blount's disease comes to mind, which is a growth plate problem in the tibia. But how common is that compared to rickets?
Also, there's idiopathic genu valgum, which is a normal variant in some children. So maybe the question is testing whether the student knows the difference between pathological and normal variants. But the options weren't provided, so I need to infer based on standard knowledge.
In many textbooks, the most common cause is indeed rickets. However, in some regions where nutrition is better, maybe Blount's disease is more common. But globally, rickets is still a leading cause. Also, other causes like osteogenesis imperfecta or other bone disorders are less common. So the correct answer here is likely rickets. The incorrect options might include Blount's disease, osteomalacia (which is adult), or Paget's disease. The explanation should clarify the difference between rickets and Blount's, and why rickets is more common.
**Core Concept**
Genu valgum (knock-knees) in children is most commonly caused by **nutritional rickets**, due to vitamin D deficiency leading to impaired bone mineralization. This results in weakened growth plates and abnormal weight-bearing forces, causing medial bowing of the tibia. Distinguishing it from idiopathic variants or structural abnormalities like Blount’s disease is critical for management.
**Why the Correct Answer is Right**
Vitamin D deficiency rickets causes hypocalcemia, secondary hyperparathyroidism, and defective osteoid mineralization. This leads to **metaphyseal widening and cupping** in the proximal tibia, resulting in a "bowtie" deformity. In early stages, genu varum may occur, but as the disease progresses, the medial tibial growth plate is disproportionately affected, causing genu valgum. Rickets remains the most frequent pathological cause in resource-limited settings.
**Why Each Wrong Option is Incorrect**
**Option A:** *Blount’s disease* is a structural growth plate disorder causing medial tibial plateau collapse but is less common than rickets.
**Option B:** *Osteogenesis imperfecta* causes generalized bone fragility but is rare and not the most common cause.
**Option C:** *Paget’s disease* occurs in adults, not children, and is unrelated to genu valgum.
**Clinical Pearl / High-Yield Fact**
In children with genu valgum, ask about **dietary vitamin D intake**, sunlight exposure, and signs of rickets (e.g., rach