**Core Concept**
The question is testing knowledge on the etiology of Avascular Necrosis (AVN) of the hip, a condition characterized by the death of bone tissue due to inadequate blood supply. AVN can result from various factors, including trauma, systemic diseases, and corticosteroid use.
**Why the Correct Answer is Right**
The most common cause of AVN of the hip is corticosteroid-induced osteonecrosis. This occurs when long-term use of corticosteroids leads to an increase in fat cells within the bone marrow, causing a decrease in the blood supply to the bone. The high fat content in the marrow makes it more susceptible to damage from corticosteroids, resulting in AVN. The femoral head is particularly vulnerable to this process due to its high fat content and relatively low blood supply.
**Why Each Wrong Option is Incorrect**
* **Option A:** Trauma is a known cause of AVN, but it is not the most common cause. Traumatic AVN often results from high-energy injuries that disrupt the blood supply to the bone.
* **Option B:** Systemic diseases such as sickle cell anemia, lupus, and rheumatoid arthritis can also cause AVN, but they are less common than corticosteroid-induced AVN.
* **Option C:** This option is empty.
**Clinical Pearl / High-Yield Fact**
It's essential to note that corticosteroids can cause AVN even at relatively low doses, and the risk increases with prolonged use. Monitoring patients on long-term corticosteroid therapy for signs of AVN is crucial.
**Correct Answer:** D. Corticosteroid use.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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