Most common cardio vascular abnormality in down syndrome is ?
Correct Answer: Endocardial cushion defect
Description: Ans. is 'b' i.e., Endocardial cushion defect About 40% of down syndrome have CHD. Endocardial cusion Atrio ventricular septal defect account for 40-60% of cases. Other feature in down syndrome. Hypotonia, flat face, upward and slanted palpebral fissures and epicanthic folds, speckled irises (Brushfield spot);varying degrees of mental and growth retardation;dysplasia of the pelvis, cardiac malformations, and simian crease;sho, broad hands, hypoplasia of middle phalanx of 5th finger, duodenal atresia, and high arched palate;5% of patients with Down syndrome are the result of a translocation-t(14q21q), t(15q21q), and t(13q21q)-in which the phenotype is the same as trisomy 21. Other feature ? Duodenal atresia Annular pancreas Tracheoesophageal fistula Hirschsprung disease Sho stature Sho sternum Brachycephaly Delayed fontanel closure Three fontanels Frontal sinus hypoplasia Peripheral joint laxity Atlantoaxial instability (C1-C2 subluxation) Exaggerated space between Mottled skin in infancy Dry coarse skin in adolescence 1st and 2nd toes Increased Risk for Development of - Leukemia:AML, ALL Myelodysplasia Transient lymphoproliferative syndrome Celiac disease Hypothyroidism Diabetes mellitus Obesity Refractive errors Strabismus Mitral valve prolapse Conductive and/or Obstructive sleep apnea Epilepsy sensorineural hearing loss ADHD Alzheimer disease Conduct oppositional disorders
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now