## **Core Concept**
The question pertains to the neurological complications associated with measles, focusing on morphological changes. Measles, caused by the measles virus, can lead to several neurological complications, including those that are morphological in nature.
## **Why the Correct Answer is Right**
Subacute sclerosing panencephalitis (SSPE) is a rare but serious complication of measles infection, occurring years after the initial measles infection. It is characterized by a chronic, progressive inflammation of the brain that leads to severe morphological changes, including demyelination and the presence of inclusion bodies within neurons and glial cells. This condition results from a persistent measles virus infection within the brain.
## **Why Each Wrong Option is Incorrect**
- **Option A:** Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating condition of the central nervous system (CNS) and can be a complication of measles infection among other viral infections. It presents with a rapid onset of widespread CNS demyelination.
- **Option B:** Measles can lead to various neurological complications, and while some are more commonly recognized, measles-associated encephalomyelitis or encephalitis does show morphological changes in the brain, such as inflammation and sometimes demyelination.
- **Option D:** Cerebellar ataxia can occur as part of the measles complications, reflecting involvement of the cerebellum.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that SSPE is a late complication of measles, occurring years after the initial infection, and it leads to severe and often fatal outcomes. The measles virus never truly clears from the body in SSPE; instead, it persists and causes progressive neurological deterioration.
## **Correct Answer:** .
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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