Molluscum contagiosum is caused by: September 2012
**Question:** Molluscum contagiosum is caused by: September 2012
**Core Concept:** Molluscum contagiosum is a common viral infection caused by the human papillomavirus (HPV) of the Molluscum contagiosum virus (MCV) genotype. There are 21 different genotypes of MCV, and the most common one associated with Molluscum contagiosum is MCV type 1.
**Why the Correct Answer is Right:** Molluscum contagiosum is caused by the human papillomavirus (HPV) belonging to the Molluscum contagiosum virus (MCV) genotype. Among the various MCV genotypes, MCV type 1 is most commonly associated with this condition. HPV is a group of more than 200 related viruses, but only a few types are known to cause skin and mucosal lesions. MCV type 1 is a member of the low-risk HPV types, which usually do not lead to malignant changes.
**Why Each Wrong Option is Incorrect:**
A. HPV type 16 and 18: These are high-risk HPV types that are associated with cervical cancer, anal cancer, and oropharyngeal cancers. They are not responsible for causing Molluscum contagiosum.
B. HPV type 6 and 11: These are also high-risk HPV types associated with anogenital warts, not Molluscum contagiosum.
C. HPV type 31 and 33: These are high-risk HPV types implicated in several cancers, not Molluscum contagiosum.
D. HPV type 36: This is a low-risk HPV type associated with condylomata acuminata (genital warts), not Molluscum contagiosum.
**Clinical Pearl:** Understanding the different HPV types is essential for accurate diagnosis and treatment. Molluscum contagiosum is a common sexually transmitted infection, primarily affecting children and immunocompromised individuals. Early diagnosis and treatment can prevent transmission to others, as the infection is easily spread through direct skin-to-skin contact.