A. 25year old woman with a obstetric score of G2P1L1 at 8 weeks with RhD negative and a non sensitized pregnancy had a spontaneous complete miscarriage. what is the dose of anti D Ig to be given to the women?

**Core Concept**
The administration of anti-D immunoglobulin (Anti-D Ig) is crucial in preventing RhD alloimmunization in RhD-negative women who may have been exposed to RhD-positive fetal blood during pregnancy or childbirth. This is particularly relevant in cases of spontaneous or induced abortion.

**Why the Correct Answer is Right**
In the event of a spontaneous complete miscarriage, the risk of fetal-maternal hemorrhage (FMH) is increased, which can lead to sensitization of the RhD-negative mother. To prevent this, Anti-D Ig is administered to neutralize any potential RhD-positive fetal blood that may have entered the maternal circulation. The standard dose of Anti-D Ig for RhD-negative women who have had a spontaneous complete miscarriage is 50 micrograms.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect as it suggests a dose that is too low to effectively prevent sensitization.
**Option B:** This option is incorrect as it suggests a dose that is too high and may lead to unnecessary side effects.
**Option C:** This option is incorrect as it does not specify the correct dose of Anti-D Ig for a spontaneous complete miscarriage.

**Clinical Pearl / High-Yield Fact**
In RhD-negative women, Anti-D Ig should be administered within 72 hours of suspected or confirmed FMH, including spontaneous or induced abortion, to prevent sensitization and subsequent alloimmunization.

**Correct Answer:** 50 **micrograms**

✓ Correct Answer: A. Anti d not required