Anaesthesia Minimum alveolar concentration (MAC) of an anesthetic agent means it produces lack of reflex response to skin incision in____ of subjects. A 25% B 50% C 75% D 100% 💡 Explanation Minimum alveolar concentration (MAC) of an anesthetic agent means it produces lack of reflex response to skin incision in____ of subjects. ✓ Correct Answer: B. 50%