Mifepristone used for medical abortion is:
## **Core Concept**
Mifepristone, also known as RU-486, is a medication used for medical abortion. It works by blocking the action of **progesterone**, a hormone essential for maintaining pregnancy. By inhibiting progesterone receptors, mifepristone prevents the continuation of pregnancy.
## **Why the Correct Answer is Right**
The correct answer, **. Mifepristone (RU-486)**, is a **progesterone receptor antagonist**. Progesterone is crucial for preparing the uterus to implant a fertilized egg and for maintaining early pregnancy. Mifepristone competes with progesterone for binding to its receptors in the uterus, effectively blocking progesterone's action. This leads to the shedding of the uterine lining and the termination of pregnancy. Mifepristone is typically used in combination with another medication, **misoprostol**, to induce labor and complete the abortion process.
## **Why Each Wrong Option is Incorrect**
- **Option A:** Incorrect because while **mifepristone** is indeed used for medical abortion, the option is not provided. However, assuming it's a distractor, any incorrect mechanism or drug not related to mifepristone's action would be wrong.
- **Option B:** Incorrect because **metoprolol**, a beta-blocker used primarily for cardiovascular diseases, has no role in medical abortion.
- **Option C:** Incorrect because **misoprostol**, although used in medical abortion, works by inducing uterine contractions and is not the primary drug that blocks progesterone receptors.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that mifepristone's effectiveness and safety for medical abortion have made it a significant drug in obstetrics. It is most effective when used within the first 50 days of pregnancy. A notable clinical correlation is that mifepristone can also be used for managing **Cushing's syndrome** due to its ability to block cortisol receptors.
## **Correct Answer:** . Mifepristone (RU-486)