Mifepristone used for inducing aboion acts on:
Correct Answer: Progesterone receptors
Description: Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol to bring about an aboion during pregnancy. This combination is 97% effective during the first 63 days of pregnancy. It is also effective in the second trimester of pregnancy. Mifepristone blocks a natural substance progesterone that is needed for pregnancy to continue. Mifepristone is a derivative of norethindrone with antiprogestin action. It binds to progesterone receptors in the endometrium and decidua, resulting in necrosis and detachment of POCs.
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Social & Preventive Medicine
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