**Core Concept**
Bone scans are essential diagnostic tools for detecting metastatic bone disease, particularly in cancer patients. This question pertains to the specific type of bone scan used for this purpose, which relies on the uptake of a radiopharmaceutical by bone metastases.

**Why the Correct Answer is Right**
The correct answer involves a bone scan that utilizes technetium-99m-methyl diphosphonate (Tc-99m MDP). This radiopharmaceutical is taken up by bone tissue, particularly in areas of increased osteoblastic activity, which is characteristic of bone metastases. The scan can help identify sites of metastatic disease, guiding further evaluation and treatment.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not relevant to the detection of metastatic bone disease. While it may be a type of bone scan, it is not the correct choice for this purpose.
* **Option B:** This option is incorrect because it does not accurately describe a bone scan used for detecting metastasis. The specific type of radiopharmaceutical and its mechanism of uptake are critical for this application.
* **Option C:** This option is not the correct choice for detecting metastatic bone disease. It may be used for other purposes, but it is not the standard for this specific application.

**Clinical Pearl / High-Yield Fact**
When interpreting bone scans, it's essential to remember that increased uptake can be seen in both osteoblastic and osteolytic lesions. However, the pattern and distribution of uptake can provide clues about the underlying pathology.

**Correct Answer:** D. Tc-99m MDP bone scan.