Mention the true/false statements about digoxin toxicity?

A. The earliest manifestation of digoxin toxicity are gastrointestinal symptoms

B. Non-specific vision changes may be noted in digoxin toxicity

C. Early toxicity may not correlate with serum levels and Neurological symptoms may occur without corresponding cardiovascular changes

D. All

Correct Answer: All

Description: Ans. All are true about digoxin toxicity.DIGOXIN TOXICITY:Features:Generally unwell & lethargy.Nausea & vomiting.Confusion.Yellow-green vision.Arrhythmias (e.g. AV block, bradycardia)Dizziness.Precipitating factors:Renal disease HypokalaemiaHypomagnesemia HypoalbuminemiaHypothermiaHypothyroidismHypercalcemia.HypernatremiaAcidosis.Myocardial ischemia.Paial AV block.Drugs:Amiodarone.Quinidine.Verapamil.Spironolactone.Furosemide.Hydrochlorothiazide - Compete with DCT secretion, hence reducing excretion.ManagementDigibind.Correct ventricular arrhythmia by lignocaine.Bradyarrhythmias by propanolol.Atrial tachyarrhythmias by atropine.Phenytoin.Monitor K+

Category: Pharmacology

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