**Core Concept**
Pyogenic meningitis is an infection of the meninges, the protective membranes surrounding the brain and spinal cord, caused by bacteria such as Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. The cerebrospinal fluid (CSF) analysis is a crucial diagnostic tool in identifying this condition.

**Why the Correct Answer is Right**
The CSF in pyogenic meningitis typically shows a high white blood cell count, primarily composed of neutrophils, with a predominance of polymorphonuclear cells. This is due to the acute inflammatory response to bacterial infection. The CSF glucose levels are also decreased, usually less than 40 mg/dL, due to bacterial consumption of glucose by the bacteria and impaired glucose transport across the blood-CSF barrier. The CSF protein levels are elevated, often greater than 100 mg/dL, reflecting the disruption of the blood-CSF barrier.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it does not specifically describe the characteristic CSF findings in pyogenic meningitis. While a high protein level is a feature, it is not the primary distinguishing feature.
**Option B:** This option is incorrect because it is too nonspecific and does not accurately describe the typical CSF findings in pyogenic meningitis.

**Clinical Pearl / High-Yield Fact**
In pyogenic meningitis, the CSF glucose levels are inversely proportional to the bacterial load, making it a useful prognostic marker. A lower CSF glucose level is associated with a worse outcome.

**Correct Answer: C.**