Which of the following is an example of a multipass membrane protein?
**Core Concept**
Multipass membrane proteins are transmembrane proteins that span the lipid bilayer multiple times, with each pass through the membrane. These proteins play crucial roles in various cellular processes, including signal transduction, transport of molecules, and enzyme activity. Examples of multipass membrane proteins include receptors, channels, and transporters.
**Why the Correct Answer is Right**
Multipass membrane proteins are characterized by their ability to span the lipid bilayer multiple times, often with specific motifs and domains that facilitate interactions with other molecules. The correct answer is an example of a multipass membrane protein that has multiple transmembrane domains, allowing it to interact with other proteins and molecules on both sides of the membrane. This protein's multipass structure enables it to perform its specific function, such as facilitating the transport of molecules across the cell membrane.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because it is a type of single-pass membrane protein, also known as a peripheral membrane protein, which interacts with the cell membrane but does not span it.
**Option B:** This option is incorrect because it is a type of soluble protein that does not interact with the cell membrane at all.
**Option C:** This option is incorrect because it is a type of lipoprotein, which is a complex of lipids and proteins, but not a multipass membrane protein.
**Clinical Pearl / High-Yield Fact**
Multipass membrane proteins are often targets for therapeutic interventions, such as drugs that bind to specific receptors or channels. Understanding the structure and function of these proteins is essential for developing effective treatments for various diseases.
**Correct Answer:** C.