Melanoma staging according to which classification
Correct Answer: Both
Description: Both REF: DeVita, Hellman, and Rosenberg's cancer: principles & practice of oncology - 8th edition Page 1908, Schwaz's Principles of Surgery 9th edition Chapter 16. The Skin and Subcutaneous Tissue The most current staging system, from the American Joint Committee on Cancer (AJCC), contains the best method of interpreting clinical information in regard to prognosis of this disease. Historically, the veical thickness of the primary tumor (Breslow thickness) and the anatomic depth of invasion (Clark level) have represented the dominant factors in the T classification. Whereas Clark used the histologic level , Breslow modified the approach to obtain a more reproducible measure of invasion by the use of an ocular micrometer. The lesions were measured from the granular layer of the epidermis or the base of the ulcer to the greatest depth of the tumor (I, 0.75 mm or less; II, 0.76 to 1.5 mm; III, 1.51 to 4.0 mm; IV, 4.0 mm or more). These levels of invasion have been subsequently modified and incorporated in the MCC staging system.
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