Megaloblastic anemia is caused by
Correct Answer: Folic acid
Description: C. i.e. (Folic acid) (377- Harsh Mohan 5th) (437- Basic pathology 8th)MEGALO BLASTIC ANEMIAS - two principal causes1. Folate deficiency (Folic acid metabolism)2. Vitamin B12 deficiency* Earliest change in PBS is appearance of hypersegmented neutrophils*** Bone marrow is markedly hypercellular* Macrocytosis (other causes - Haemolysis, liver disease, alcoholism, hypothyroidism**, aplastic anaemia, myeloproliferative disorders and reticulocytosis)* ** MCV |, MCH|, MCHC Normal or |* **SHILLING TEST for Vitamin Bj2 deficiency* FIGLU TEST for folate deficiency* The gene responsible for folic acid transport is situated on chromosome 21**
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now