## **Core Concept**
Cutaneous mechanoreceptors are specialized sensory receptors in the skin that respond to mechanical stimuli, such as pressure, stretch, and vibration. There are several types of mechanoreceptors, each with distinct properties and sensitivities to different types of stimuli. The question focuses on the type of mechanoreceptor best suited to detect vibrations in the 60-300 Hz range.

## **Why the Correct Answer is Right**
The correct answer, **Pacinian corpuscles**, are rapidly adapting mechanoreceptors that are highly sensitive to high-frequency vibration and pressure changes. They are found in the dermal and hypodermal layers of the skin and are known for their ability to detect vibration in the range of 60-300 Hz. This sensitivity range makes them particularly effective at encoding information about high-frequency vibrations.

## **Why Each Wrong Option is Incorrect**
- **Option A (Meissner's corpuscles):** These are rapidly adapting mechanoreceptors sensitive to light touch and low-frequency vibration (5-50 Hz), making them less suitable for detecting vibrations at 60-300 Hz.
- **Option B (Merkel's discs):** These are slowly adapting mechanoreceptors involved in detecting sustained pressure and texture. They are not specialized for high-frequency vibration detection.
- **Option D (Ruffini's corpuscles):** These are slowly adapting mechanoreceptors that respond to skin stretch and are involved in detecting slip of skin over a surface. They are not specifically tuned to high-frequency vibrations.

## **Clinical Pearl / High-Yield Fact**
A key point to remember is that **Pacinian corpuscles** are responsible for the detection of vibration. This is a critical sensory function that allows individuals to perceive and interpret their environment accurately. Damage to these receptors or their pathways can result in impaired vibration sense, which is a common finding in certain neurological conditions.

## **Correct Answer:** . Pacinian corpuscles.