Pharmacology Mechanism of action of vincristine in the treatment of ALL is: A Inhibition of topoisomerase II to cause breaks in DNA strands B Alkylation and cross linking DNA strands C Inhibition of DNA mediated RNA synthesis D Inhibition of polymerization of tubulin to form microtubules π‘ Explanation Mechanism of action of vincristine in the treatment of ALL is: β Correct Answer: D. Inhibition of polymerization of tubulin to form microtubules