Pharmacology Mechanism of action of tetracycline is – A Binds to A site and inhibit attachment of t-RNA. B Inhibits peptidyl transferase C Causes misreading of mRNA D Causes termination of peptide chain elongation 💡 Explanation Mechanism of action of tetracycline is - ✓ Correct Answer: A. Binds to A site and inhibit attachment of t-RNA.