Mechanism of action of oral contraceptive pill can be all except ?
**Core Concept:** Oral contraceptive pills are a combination of estrogen and progestogen hormones that suppress ovulation, thicken cervical mucus to prevent sperm entry, and alter endometrial growth to make it less hospitable for implantation.
**Why the Correct Answer is Right:** Oral contraceptive pills (OCP) work by mimicking the effects of natural hormones in the body, specifically estrogen and progestogen. The two primary mechanisms through which OCP exert their contraceptive effects are:
1. **Suppression of ovulation:** OCP increase the sensitivity of the hypothalamus and pituitary gland to gonadotropin-releasing hormone (GnRH), which results in a decrease in luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion. This suppression of LH and FSH prevents the development of ovarian follicles and ultimately prevents ovulation.
2. **Alteration of cervical mucus and endometrium:** OCP increase the thickness of cervical mucus, making it more difficult for sperm to penetrate and reach the uterus. Additionally, OCP affect the endometrium by reducing its receptivity to implantation, reducing the chance of successful fertilization.
The correct answer, **A, B, and D**, are all mechanisms by which OCP exert their contraceptive effects. Therefore, option C ("Increase blood flow to the breast") is the correct answer as it does not directly contribute to the primary mechanisms of action mentioned above.
**Why Each Wrong Option is Incorrect:**
**Option A (Increase blood flow to the breast):** While OCP can cause some side effects like breast tenderness or gynecomastia, this is not a primary mechanism of action. The primary mechanism of action relates to suppression of ovulation, thickening of cervical mucus, and alteration of endometrium, not breast blood flow.
**Option B (Increase blood flow to the skin):** Similar to option A, increased blood flow to the skin is a side effect and not a primary mechanism of action for OCP. The primary mechanisms focus on suppressing ovulation and affecting cervical mucus and endometrium.
**Option C (Increase blood flow to the breast):** As mentioned above, this is a side effect, not a mechanism of action, making it irrelevant to the primary mechanisms of action.
**Option D (Increase blood flow to the uterus):** Similarly to options A and C, increased blood flow to the uterus is a side effect and not a primary mechanism of action for OCP. The primary mechanisms focus on suppressing ovulation, thickening cervical mucus, and altering endometrium.
**Core Concept:** Oral contraceptive pills (OCP) are a type of hormonal contraceptive that contains synthetic estrogen and progestin hormones which mimic the effects of these hormones naturally produced by the ovaries. The primary mechanisms of action of OCP include:
1. Suppression of ovulation: OCP suppress ovulation by increasing the sensitivity of the hypothalamus and pituitary gland to GnRH, which in turn reduces