Medical MCQ-Mechanism of action of ciprofloxacin in gram negative bacteria:-

Mechanism of action of ciprofloxacin in gram negative bacteria:-

Inhibition of mycolic acid

Inhibition of topoisomerase IV

Inhibition of DNA gyrase

Inhibition of helicase

Question Category:

Pharmacology

Correct Answer:

Inhibition of DNA gyrase

Description:

MECHANISM OF FLUOROQUINOLONES (FQ) In gram negative bacteria, FQ inhibit DNA gyrase by binding to its A subunit and interfere with cutting and resealing function. In gram positive bacteria, FQ inhibit similar enzyme DNA topoisomerase IV.

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