Mechanism of action of ciprofloxacin in gram negative bacteria:-

Correct Answer: Inhibition of DNA gyrase
Description: MECHANISM OF FLUOROQUINOLONES (FQ) In gram negative bacteria, FQ inhibit DNA gyrase by binding to its A subunit and interfere with cutting and resealing function. In gram positive bacteria, FQ inhibit similar enzyme DNA topoisomerase IV.
Category: Pharmacology
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