Pharmacology Mechanism of action of buspirone is? A 5 HT1A paial agonism. B 5 HT1B antagonism. C 5 HT1B paial agonism. D 5 HT2C antagonism. 💡 Explanation Mechanism of action of buspirone is? ✓ Correct Answer: A. 5 HT1A paial agonism.