**Core Concept:** The question is about ethical principles guiding healthcare professionals in their interactions with patients. The options provided are the principles ensuring patient autonomy, confidentiality, and informed consent.

**Why the Correct Answer is Right:** The principle of informed consent requires healthcare professionals to fully inform patients about their medical condition, treatment options, and potential risks and benefits before obtaining their consent for the procedure or treatment. In this context, the correct answer is **Option D: Informed Consent**.

**Why Each Wrong Option is Incorrect:**

**Option A (Respect for Autonomy):** Respect for autonomy involves respecting a patient's right to make decisions regarding their healthcare. While this is an important principle, it does not solely focus on providing information to the patient.

**Option B (Non-Maleficence):** Non-maleficence refers to avoiding harm and minimizing complications, but it does not directly involve informing patients about their condition or treatment options.

**Option C (Beneficence):** Beneficence is about doing good for the patient, which includes providing beneficial treatment but does not solely focus on patient education and informed decision-making.

**Option E (Justice):** Justice pertains to fair distribution of healthcare resources and ensuring equal access, which is not directly related to patient education and informed decision-making.

**Clinical Pearl / High-Yield Fact:** Informed consent is a critical principle in healthcare ethics, as it ensures patients are well-informed and can make informed choices about their healthcare, which fosters patient autonomy and trust in the healthcare team.

**Correct Answer:** **Option D (Informed Consent)** is the right answer because it directly addresses the responsibility of healthcare professionals to provide patients with sufficient information to make informed decisions about their care. This principle helps protect patient autonomy and ensures appropriate treatment choices based on the patient's values, preferences, and understanding of their condition and treatment options.