**Core Concept**
The question is testing the understanding of beta-hemolytic streptococci, specifically Group A Streptococcus (GAS), which is known for causing skin infections like impetigo and pharyngitis. Beta-hemolysis refers to the complete breakdown of red blood cells in agar cultures, resulting in a clear or transparent zone around bacterial colonies.
**Why the Correct Answer is Right**
The presence of beta-hemolysis in skin ulcer and sore throat cultures indicates that both infections are caused by Group A Streptococcus (GAS). GAS can cause skin infections, such as impetigo, and pharyngitis, which is characterized by a sore throat. The similarity between both cases lies in the fact that GAS can cause a range of infections, including skin and soft tissue infections, as well as respiratory tract infections.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option might be a distractor, but it does not directly relate to the similarity between skin ulcer and sore throat caused by beta-hemolytic streptococci.
* **Option B:** This option might be a distractor, but it does not directly relate to the similarity between skin ulcer and sore throat caused by beta-hemolytic streptococci.
* **Option D:** This option might be a distractor, but it does not directly relate to the similarity between skin ulcer and sore throat caused by beta-hemolytic streptococci.
**Clinical Pearl / High-Yield Fact**
Group A Streptococcus (GAS) can cause a range of infections, including skin infections, pharyngitis, and Scarlet fever. GAS is also responsible for post-streptococcal glomerulonephritis (PSGN), a complication of streptococcal pharyngitis.
**Correct Answer: C. Both conditions are caused by Group A Streptococcus (GAS).**
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