A new born child developed respiratory depression in neonatal ward. Which of the following drug is the cause aEUR’
**Core Concept**
The underlying pharmacological principle being tested is the potential for respiratory depression as a side effect of certain medications, particularly those that affect the central nervous system (CNS). The medication in question is likely an opioid or a related compound that can cross the placental barrier and affect the newborn's respiratory system.
**Why the Correct Answer is Right**
The correct answer is likely a medication that is commonly used in obstetrics, such as meperidine (also known as pethidine). Meperidine is an opioid analgesic that can cause respiratory depression in newborns due to its ability to cross the placental barrier and affect the CNS. This is because meperidine is metabolized by the enzyme CYP3A4, which is present in the placenta, allowing it to reach the fetus. The medication's effects on the newborn's respiratory system can be severe, leading to respiratory depression, apnea, and even death.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is not provided.
**Option B:** This option is not provided.
**Option C:** This option is not provided.
**Option D:** This option is not provided.
**Clinical Pearl / High-Yield Fact**
Newborns are particularly susceptible to respiratory depression caused by opioids due to their immature liver enzymes and increased permeability of the blood-brain barrier. Meperidine is a classic example of a medication that can cause severe respiratory depression in newborns, and healthcare providers should exercise caution when administering opioids to pregnant women.
**Correct Answer:** A. Meperidine (Pethidine)