## **Core Concept**
The question presents a clinical scenario involving an elderly patient with a combination of symptoms including prosopagnosia (face blindness), memory loss, third-person hallucinations, increased deep tendon reflexes, and a mini-mental examination score of 20/30. These symptoms collectively point towards a neurodegenerative disorder affecting cognitive and perceptual functions.
## **Why the Correct Answer is Right**
The correct answer, **Dementia with Lewy Bodies (DLB)**, is supported by the presence of visual hallucinations (third-person hallucinations can be considered a form of complex visual hallucination), fluctuations in cognitive function (not directly mentioned but can be inferred from the progression), and changes in personality and behavior. DLB is characterized by the presence of **Lewy bodies** (abnormal protein clumps) in the brain, which are associated with **alpha-synuclein** pathology. The symptoms described, particularly the early and prominent visual hallucinations and prosopagnosia, are more suggestive of DLB than other forms of dementia.
## **Why Each Wrong Option is Incorrect**
- **Option A:** Alzheimer's disease is a primary cause of dementia but typically presents with more pronounced memory loss and less commonly with early visual hallucinations or prosopagnosia as primary symptoms.
- **Option B:** Frontotemporal dementia can present with significant changes in personality, behavior, and language but usually does not have the combination of prosopagnosia, significant visual hallucinations, and increased deep tendon reflexes as early features.
- **Option C:** Vascular dementia might present with a more stepwise progression of cognitive decline and focal neurological signs due to specific vascular events, which are not mentioned in the scenario.
## **Clinical Pearl / High-Yield Fact**
A key clinical pearl in this case is the importance of recognizing **visual hallucinations** as an early and significant symptom. In dementia, the presence of visual hallucinations, especially within the first year, is highly suggestive of Dementia with Lewy Bodies. This condition is often underdiagnosed and can be confused with Alzheimer's disease or other forms of dementia.
## **Correct Answer: D. Dementia with Lewy Bodies.**
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
Access thousands of free MCQs, ebooks and daily exams.
By signing in you agree to our Privacy Policy.