Maximum Lattice formation occurs in –
Correct Answer: Zone of equivalence
Description: Ans. is 'c' i.e., Zone of equivalence o The lattice hypothesis was proposed by marrack (1934) to explain the mechanism of precipitationo According to this concept, multivalent antigens combine with bivalent antibodies in varying proportion depending on the antigen-antibody ratio in the reacting mixture.o Precipitation results when large lattice is formed consisting of alternating antigen and antibody molecules. This is possible only in the zone of equivalence.o In the zone of antigen or antibody excess, the lattice does not enlarge, as the valencies of the antibody and the antigen, repectively are fully satisfied. In either cases extensive lattice cannot be formed and precipition is inhibitedo The lattice hypothesis holds good for agglutination also.
Category:
Microbiology
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