Marker of peroxisomes is
## Core Concept
Peroxisomes are organelles found in cells that are involved in the catabolism of fatty acids and amino acids. One of the key functions of peroxisomes is to break down fatty acids through beta-oxidation, which shortens the fatty acid chains. This process is crucial for the metabolism of certain lipids.
## Why the Correct Answer is Right
The correct answer, **C. Catalase**, is a marker enzyme for peroxisomes because catalase is a key enzyme located within peroxisomes. Catalase catalyzes the decomposition of hydrogen peroxide to water and oxygen, playing a critical role in protecting the cell from oxidative damage. This enzyme is specifically localized to peroxisomes, making it a reliable marker for these organelles.
## Why Each Wrong Option is Incorrect
- **Option A:** This option is incorrect because while various enzymes are associated with different organelles, without the specific enzyme listed, it's hard to directly refute. However, we know that catalase is a definitive marker.
- **Option B:** This option is incorrect as it does not specify an enzyme that is uniquely associated with peroxisomes.
- **Option D:** This option is incorrect because, similar to option B, without specifying an enzyme, it's hard to assess directly. However, the focus is on catalase as a peroxisomal marker.
## Clinical Pearl / High-Yield Fact
A key clinical correlation is that peroxisomal biogenesis disorders (PBDs), such as Zellweger syndrome, are associated with defects in peroxisome formation and function. These disorders can lead to severe neurological and developmental impairments. Catalase deficiency or dysfunction can also lead to increased oxidative stress within cells.
## Correct Answer: C. Catalase