Pharmacology Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules A Are first messengers B Activate phospholipase C C Are derived from PIP2 D Can't activate calcium calmodulin-dependent protein kinases directly or indirectly 💡 Explanation Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules ✓ Correct Answer: C. Are derived from PIP2