Many drugs are used as rescue therapy for preventing the adverse effects of anticancer drugs. Folinic acid is used in:-

A. Methotrexate toxicity

B. Cisplatin toxicity

C. Doxorubicin toxicity

D. Cyclophosphamide toxicity

Correct Answer: Methotrexate toxicity

Description: DHF | DHF reductase<-------- inhibited by METHOTREXATE THF/FOLINILACID/LEVCOVORIN Thereforeto treat MTX toxicity FOLINIC ACID/LEVCOVORIN is used. B: Cisplatin Vomiting d/tcisplatin :ONDANSETRON Nephrotoxicity :AMIFOSTINE C: cardiotoxicity d/t doxorubicin : DEXRAZOXANE D: hemorrhagic cystitis d/t cyclophosphamide : MESNA

Category: Pharmacology

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