**Core Concept**
A pancreatic abscess is a collection of pus in the pancreas, often resulting from pancreatic necrosis or infection. Management involves prompt drainage to prevent further complications and sepsis.

**Why the Correct Answer is Right**
The correct management of a pancreatic abscess is percutaneous drainage under imaging guidance, typically ultrasound or CT-guided. This approach allows for direct access to the abscess, enabling the removal of pus and potentially infected pancreatic tissue. The procedure is often performed in conjunction with antibiotics to address any underlying infection.

**Why Each Wrong Option is Incorrect**
**Option A:** Surgical drainage, while sometimes necessary, is not the first-line approach due to the risks associated with surgery in critically ill patients.
**Option B:** Antibiotics alone are insufficient for managing a pancreatic abscess, as the collection of pus requires direct drainage to resolve.
**Option C:** Endoscopic drainage may be considered in selected cases, but percutaneous drainage remains the preferred method for most pancreatic abscesses.

**Clinical Pearl / High-Yield Fact**
In cases of suspected pancreatic abscess, early imaging with ultrasound or CT scan is crucial for prompt diagnosis and initiation of management.

**Correct Answer:** C. Percutaneous drainage under imaging guidance.