**Core Concept**
Epidural abscess is a collection of pus in the epidural space surrounding the spinal cord, which can lead to neurological compromise and potentially life-threatening complications. Prompt and effective management is essential to prevent long-term damage and minimize morbidity and mortality.

**Why the Correct Answer is Right**
The management of epidural abscess typically involves a multidisciplinary approach, including surgical drainage, antibiotics, and close monitoring of neurological function. The primary goal is to remove the source of infection and restore the integrity of the epidural space. This may involve laminectomy or a minimally invasive approach to drain the abscess, followed by intravenous antibiotics to target the causative organism.

**Why Each Wrong Option is Incorrect**
**Option A:** Antibiotics alone may not be sufficient to manage epidural abscess, as the infection may not penetrate the epidural space effectively.
**Option B:** Conservative management without surgical intervention can lead to delayed diagnosis and treatment, resulting in increased morbidity and mortality.
**Option C:** Tissue plasminogen activator (tPA) is not indicated in the management of epidural abscess, as it does not address the underlying infection or inflammation.

**Clinical Pearl / High-Yield Fact**
In the setting of suspected epidural abscess, a high index of suspicion and prompt imaging studies (e.g., MRI or CT myelogram) are crucial to establish the diagnosis and guide timely intervention.

**Correct Answer:** C. Surgical drainage and antibiotics.