**Question:** A 55-year-old woman was found to have Ca cervix, FIGO stage 2-3, locally advanced. What would be the management?

**Core Concept:** Locally advanced cervical cancer refers to tumors that have invaded the cervix or surrounding tissues, potentially affecting the vagina, urethra, or rectum. FIGO staging system is used to classify cervical cancer based on its extent. Stage 2-3 indicates that the tumor has spread beyond the cervix but not involving nearby organs.

**Why the Correct Answer is Right:**

For locally advanced cervical cancer, the management typically involves a combination of surgery, radiation therapy, and chemotherapy. In this case, the correct answer (C) refers to a multimodal approach that combines surgery, radiation, and chemotherapy.

1. **Option A (Surgery alone):** Surgery alone may not be sufficient for stage 2-3 cervical cancer due to the risk of tumor recurrence and residual disease. Combining surgery with other modalities is necessary for optimal treatment outcomes.
2. **Option B (Radiation Therapy alone):** While radiation therapy can be beneficial in controlling local tumor growth, it may not eliminate the possibility of distant spread or tumor recurrence. Combining radiation therapy with surgery and chemotherapy increases the chances of successful treatment.
3. **Option D (Chemotherapy alone):** Chemotherapy can be used in the management of locally advanced cervical cancer, particularly for palliation or reducing tumor bulk before surgery. However, chemotherapy alone may not be sufficient to eradicate the disease completely due to the tumor's size and spread.

**Why Each Wrong Option is Incorrect:**

Option A, B, and D all focus on individual treatment modalities that may not provide adequate control of the disease. Combining these modalities (option C) is crucial to address the local tumor growth, potential distant spread, and reduce the risk of tumor recurrence.

**Clinical Pearl:** Multimodal treatment approaches, such as combining surgery, radiation therapy, and chemotherapy, are essential for optimal management of locally advanced cervical cancer (FIGO stage 2-3) to achieve a higher chance of complete eradication of the disease and improve overall survival rates.