Okay, so I need to figure out the answer to this question about Mallory bodies. The question is asking which condition does NOT show Mallory bodies. Let me start by recalling what Mallory bodies are.

Mallory bodies, also known as Mallory-Denk bodies, are intracellular inclusions found in liver cells (hepatocytes). They are composed of aggregated intermediate filaments, primarily keratin 8 and 18. These structures are a histological hallmark of alcoholic liver disease, especially alcoholic hepatitis. But they can also be present in other liver conditions.

Now, the question is about which condition is an exception. Let me think of the common conditions associated with Mallory bodies. Alcoholic liver disease is a big one. Then there's non-alcoholic steatohepatitis (NASH), which is part of non-alcoholic fatty liver disease (NAFLD). Autoimmune hepatitis can also show Mallory bodies. Wilson's disease is another possibility, as it's a metabolic disorder that affects the liver and can lead to similar histological findings. But wait, what about viral hepatitis? For example, hepatitis B or C—do they show Mallory bodies? I think Mallory bodies are not typically a feature of viral hepatitis. They are more specific to the conditions I mentioned earlier.

So if the options include viral hepatitis, that might be the correct answer here. Let me check the options again. Wait, the user didn't list the actual options, but in the original question, the correct answer is supposed to be the exception. Assuming the options are something like Alcoholic hepatitis, NASH, Autoimmune hepatitis, and Viral hepatitis B. Then the answer would be Viral hepatitis B.

But I need to make sure. Let me confirm: Mallory bodies are indeed seen in alcoholic liver disease, NASH, autoimmune hepatitis, and Wilson's disease. In viral hepatitis, especially acute forms, the histological features are different—like ballooning degeneration, Councilman bodies, and inflammatory infiltrates, but not Mallory bodies. So if one of the options is viral hepatitis, that's the exception.

Another possible exception could be something like hemochromatosis or alpha-1 antitrypsin deficiency, but I think Mallory bodies can also appear in those. Wait, no—those might have other features, but Mallory bodies aren't characteristic. Hmm, maybe I'm mixing up. Let me verify. Mallory bodies are a feature of conditions with chronic liver injury, especially those involving alcohol or metabolic factors. Viral hepatitis, unless it's chronic and leading to cirrhosis, might not have Mallory bodies. So if the options are Alcoholic hepatitis, NASH, Autoimmune hepatitis, and Viral hepatitis B, then the answer is Viral hepatitis B.

So the correct answer is the one that's not associated with Mallory bodies. Therefore, the exception is viral hepatitis.

**Core Concept** Mallory-Denk bodies are eosinophilic cytoplasmic inclusions in hepatocytes, composed of keratin filaments. They are classic histological features of chronic liver injury, particularly **alcoholic hepatitis**, **non-alcoholic steatohepatitis (NASH)**, and **autoimmune hepatitis**. Their absence in certain conditions can help differentiate liver diseases.

**Why the Correct Answer is Right** Viral hepatitis (e.g., hepatitis B or

✓ Correct Answer: C. Secondary biliary cirrhosis