Mallory bodies are seen in all of the following conditons except
Correct Answer: Secondary biliary cirrhosis
Description: Mallory bodies or alcoholic hyalin: These are eosinophilic, intracytoplasmic inclusions seen in perinuclear location within swollen and ballooned hepatocytes. They represent aggregates of cytoskeletal intermediate filaments (prekeratin). They can be best visualised with connective tissue stains like Masson's trichrome and chromophobe aniline blue, or by the use of immunoperoxidase methods. Mallory bodies are highly suggestive of, but not specific for, alcoholic hepatitis since Mallory bodies are also found in ceain other conditions such as: primary biliary cirrhosis, Indian childhood cirrhosis, cholestatic syndromes, Wilson's disease, intestinal bypass surgery, focal nodular hyperplasia and hepatocellular carcinoma. TEXTBOOK OF PATHOLOGY 6TH EDITION HARSH MOHAN PAGE NO:621,622
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