Malignant peripheral nerve sheath tumour showing which of the following differentiation is termed as “Triton tumour”?
Correct Answer: Rhabdomyoblastic
Description: An interesting phenomenon observed in malignant peripheral nerve sheath tumour (MPNST) is described as "divergent differentiation." This term refers to the presence of focal areas that exhibit other lines of differentiation, including glandular, cailaginous, osseous (bone), or rhabdomyoblastic (striated muscle) morphology. MPNST exhibiting the rhabdomyoblastic differentiation is referred to as Triton tumour. Most MPNSTs (approximately 85%) are high-grade tumors. Most are associated with larger peripheral nerves in the chest, abdomen, pelvis, neck, or limb-girdle. Typical cases show a fasciculated arrangement of spindle shaped tumour cells.
Category:
Pathology
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