All of the following are the markers for malignant germ cell tumors of ovary except :
**Core Concept**
Malignant germ cell tumors of the ovary are a type of cancer that arises from the germ cells of the ovary. These tumors can be classified into different subtypes, including dysgerminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, and mature teratoma with malignant transformation. The markers for these tumors are often used in the diagnosis and management of the disease.
**Why the Correct Answer is Right**
The markers for malignant germ cell tumors of the ovary include alpha-fetoprotein (AFP), beta-human chorionic gonadotropin (β-hCG), and lactate dehydrogenase (LDH). AFP is elevated in yolk sac tumors and embryonal carcinomas, while β-hCG is elevated in choriocarcinomas. LDH is a more general marker that can be elevated in various types of germ cell tumors.
**Why Each Wrong Option is Incorrect**
* **Option A:** This option is incorrect because the marker for this type of tumor is not specific to malignant germ cell tumors of the ovary.
* **Option B:** This option is incorrect because the marker for this type of tumor is not commonly used in the diagnosis of malignant germ cell tumors of the ovary.
* **Option C:** This option is incorrect because the marker for this type of tumor is not typically elevated in malignant germ cell tumors of the ovary.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the markers for malignant germ cell tumors of the ovary can vary depending on the subtype of the tumor. A high index of suspicion and a thorough diagnostic workup are necessary to accurately diagnose and manage these patients.
**Correct Answer: D.**