Medical MCQ - Malignancy is typically associated with disordered differentiation and mutation .which of the following mentioned options best describes anaplasia

Malignancy is typically associated with disordered differentiation and mutation .which of the following mentioned options best describes anaplasia

Hepatic tumor cells synthesizing bile

Skin tumor cells producing keratin pearls

Bronchial epithelial cells producing keratin pearls

Muscle tumor cells forming giant cells

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Correct Answer:

Muscle tumor cells forming giant cells

Description:

Neoplastic cells may be. Similar to normal cells found in the tissue of origin, which defines the malignancy as well differentiated or low grade. Alternatively the neoplastic cells may lack most of the characteristics of normal cells found in the tissue of origin ,which defines the malignancy as poorly differentiated or high grade . Tumor that contain neoplastic cells in the midst of this spectrum are termed moderately differentiated or medium grade.anaplastic means complete lack of differentiation

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