Which of the following infestations lead to malabsorption: March 2011
**Core Concept**
The question is testing the ability to identify an infestation that leads to malabsorption. Malabsorption occurs when the body is unable to properly absorb nutrients from food, often due to a disruption in the normal functioning of the gastrointestinal (GI) tract.
**Why the Correct Answer is Right**
Whipworm (Trichuris trichiura) infestation can lead to malabsorption due to the physical damage it causes to the intestinal mucosa. The whipworm's presence in the large intestine can lead to chronic inflammation, ulceration, and bleeding, which can impair the normal functioning of the intestinal epithelium. As a result, the body's ability to absorb essential nutrients is compromised.
**Why Each Wrong Option is Incorrect**
* **Option A:** Hookworm infestation primarily leads to iron deficiency anemia due to chronic blood loss, rather than malabsorption.
* **Option B:** Roundworm (Ascaris lumbricoides) infestation can lead to intestinal obstruction, but it is not typically associated with malabsorption.
* **Option D:** Tapeworm infestation can lead to malabsorption, but it is not the most common or characteristic infestation associated with this symptom.
**Clinical Pearl / High-Yield Fact**
When considering the impact of infestations on the GI tract, remember that whipworm infestation is a classic cause of malabsorption due to its direct physical damage to the intestinal mucosa.
**Correct Answer: C. Whipworm infestation can lead to malabsorption due to its direct physical damage to the intestinal mucosa.**