Magnesium is not involved in ?
Correct Answer: Increased neuromuscular excitability
Description: Ans. is 'c' i.e., Increased neuromuscular excitability Biochemical functions of magnesium o Impoant function of magnesium are :?1. Enzyme activationMagnesium activates a number of enzymes, paicularly in which ATP-Mg" is a substrate, i.e. phosphate transferring enzymes.The enzymes needing magnesium are involved in intermediary metabolism, transcellular ion transpo, muscle contraction and oxidative phosphorylation.Impoant examples of such enzymes are hexokinase, phosphofructokinase, pyruvate kinase, Glucose-6- phosphatase, enolase, creatine kinase, other phosphatases and kinases, adenylate cyclase, glutamine synthase, thiokinase, squalene synthase etc.2. Neuromuscular excitibilityNeuromuscular excitibility is decreased by magnesium, therefore, a decrease in magnesium level results in increased nerve excitibility.3. OtherMagnesium improves glucose tolerance, probably by enhancing insulin dependent glucose uptake.Magnesium is a constituent of bone & teeth.Magnesium binds to other nucleoside phosphates and nucleic acids and is required for DNA replication, transcription and translation.The DNA helix is stabilized by binding of histones and magnesium to the exposed phosphate groups.
Category:
Biochemistry
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